The research result on Ni-catalyzed Desulfonylative Suzuki–Miyaura Cross-Coupling of Unactivated Aryl Sulfones  has been published in ACS Catalysis.

doi/10.1021/acscatal.5c02609

We have successfully developed a Ni-catalyzed Suzuki-Miyaura cross-coupling reaction via carbon-sulfur bond cleavage of arylsulfones. Aryl sulfones have rarely been used as substrates for cross^coupling reactions because of their chemical stability, but this study shows that this limitation can be overcome by Ni catalyst. Interestingly, the Ni catalyst was found to react preferentially with aryl sulfones over generally reactive aryl halides.This reversal of reactivity is a rare phenomenon in cross-coupling chemistry. By utilizing our method, sequential transformations have become possible, and we have demonstrated a new synthetic strategy that have been difficult to synthesize by previous methods.

Congratulations, Ryusei!

This research was conducted in collaboration with Dr. Yokokawa (The University of Tokyo).

Press release articles at the University

https://www.nagoya-u.ac.jp/researchinfo/result/2025/05/post-829.html